Pure Appl. Chem., 2000, Vol. 72, No. 7, pp. 1207-1228
http://dx.doi.org/10.1351/pac200072071207
Synthetic pathways and processes in green chemistry. Introductory overview
            Abstract:
            
          
        
        
	
            
    Contents
- Green Chemistry in the International Context
 - The Concept of green Chemistry 
Definition of green chemistry | Green chemistry: Why now? | The historical context of green chemistry | The emergence of green chemistry - The Content of Green Chemistry 
Areas of green chemistry | Preliminary remarks | Alternative feedstocks | Benign reagents/synthetic pathways | Synthetic transformations | Solvents/reaction conditions 
Green Chemistry in the International Context
          It has come to be recognized in recent years, that the science of chemistry 
          is central to addressing the problems facing the environment. Through 
          the utilization of the various subdisciplines of chemistry and the molecular 
          sciences, there is an increasing appreciation that the emerging area 
          of green chemistry1
          is needed in the design and attainment of sustainable development. A 
          central driving force in this increasing awareness is that green chemistry 
          accomplishes both economic and environmental goals simultaneously through 
          the use of sound, fundamental scientific principles. 
        
Recently, a basic strategy has been proposed for implementing the relationships 
          between industry and academia, and hence, funding of the research that 
          constitutes the engine of economic advancement; it is what many schools 
          of economics call the "triple bottom line" philosophy, 
          meaning that an enterprise will be economically sustainable if the objectives 
          of environmental protection, societal benefit, and market advantage 
          are all satisfied2. 
          Triple bottom line is a strong idea for evaluating the success of environmental 
          technologies. It is clear that the best environmentally friendly technology 
          or discovery will not impact on the market if it is not economically 
          advantageous; in the same way, the market that ignores environmental 
          needs and human involvement will not prosper. This is the challenge 
          for the future of the chemical industry, its development being strongly 
          linked to the extent to which environmental and human needs can be reconciled 
          with new ideas in fundamental research. On the other hand, it should 
          be easy to foresee that the success of environmentally friendly reactions, 
          products, and processes will improve competitiveness within the chemical 
          industry. If companies are able to meet the needs of society, people 
          will influence their own governments to foster those industries attempting 
          such environmental initiatives. Of course, fundamental research will 
          play a central role in achieving these worthy objectives. What we call 
          green chemistry may in fact embody some of the most advanced perspectives 
          and opportunities in chemical sciences.
          It is for these reasons that the International Union of Pure and Applied 
          Chemistry (IUPAC) has a central role to play in advancing and promoting 
          the continuing emergence and impact of green chemistry. When we think 
          about how IUPAC furthers chemistry throughout the world, it is useful 
          to refer to IUPAC's Strategic Plan. This plan demonstrates the direct 
          relevance of the mission of IUPAC to green chemistry, and explains why 
          there is growing enthusiasm for the pursuit of this new area as an appropriate 
          activity of a scientific Union. The IUPAC Strategic Plan outlines among 
          other goals:
        - IUPAC will serve as a scientific, international, nongovernmental body in objectively addressing global issues involving the chemical sciences. Where appropriate, IUPAC will represent the interests of chemistry in governmental and nongovernmental forums.
 - IUPAC will provide tools (e.g., standardized nomenclature and methods) and forums to help advance international research in the chemical sciences.
 - IUPAC will assist chemistry-related industry in its contributions to sustainable development, wealth creation, and improvement in the quality of life.
 - IUPAC will facilitate the development of effective channels of communication in the international chemistry community.
 - IUPAC will promote the service of chemistry to society in both developed and developing countries.
 - IUPAC will utilize its global perspective to contribute toward the enhancement of education in chemistry and to advance the public understanding of chemistry and the scientific method.
 - IUPAC will make special efforts to encourage the career development of young chemists.
 - IUPAC will broaden the geographical base of the Union and ensure that its human capital is drawn from all segments of the world chemistry community.
 - IUPAC will encourage worldwide dissemination of information about the activities of the Union.
 - IUPAC will assure sound management of its resources to provide maximum value for the funds invested in the Union.
 
Through the vehicle of green chemistry, IUPAC can engage and is engaging 
          the international community in issues of global importance to the environment 
          and to industry, through education of young and established scientists, 
          the provision of technical tools, governmental engagement, communication 
          to the public and scientific communities, and the pursuit of sustainable 
          development. By virtue of its status as a leading and internationally 
          representative scientific body, IUPAC is able to collaborate closely 
          in furthering individual national efforts as well as those of multinational 
          entities.
        An important example of such collaboration in the area of green chemistry 
          is that of IUPAC with the Organization for the Economical Cooperation 
          and Development (OECD) in the project on "Sustainable Chemistry", aimed 
          at promoting increased awareness of the subject in the member countries. 
          During a meeting of the Environment Directorate (Paris, 6 June 1999), 
          it was proposed that United States and Italy co-lead the activity, and 
          that implementation of five recommendations to the member countries 
          be accorded the highest priority, namely:
	  - research and development
 - awards and recognition for work on sustainable chemistry
 - exchange of technical information related to sustainable chemistry
 - guidance on activities and tools to support sustainable chemistry programs
 - sustainable chemistry education
 
These recommendations were perceived to have socio-economic implications 
          for worldwide implementation of sustainable chemistry. How IUPAC and, 
          in particular, its Divisions can contribute to this effort is under 
          discussion. IUPAC is recognized for its ability to act as the scientific 
          counterpart to OECD for all recommendations and activities. Although 
          the initiatives being developed by the OECD are aimed primarily at determining 
          the role that national institutions can play in facilitating the implementation 
          and impact of green chemistry, it is recognized that each of these initiatives 
          also has an important scientific component. Whether it is developing 
          criteria or providing technical assessment for awards and recognition, 
          identifying appropriate scientific areas for educational incorporation, 
          or providing scientific insight into the areas of need for fundamental 
          research and development, IUPAC can play and is beginning to play an 
          important role as an international scientific authority on green chemistry.
        Other multinational organizations including, among others, the United 
          Nations, the European Union, and the Asian Pacific Economic Community, 
          are now beginning to assess the role that they can play in promoting 
          the implementation of green chemistry to meet environmental and economic 
          goals simultaneously. As an alternative to the traditional regulatory 
          framework often implemented as a unilateral strategy, multinational 
          governmental organizations are discovering that green chemistry as a 
          nonregulatory, science-based approach, provides opportunities for innovation 
          and economic development that are compatible with sustainable development. 
          In addition, individual nations have been extremely active in green 
          chemistry and provide plentiful examples of the successful utilization 
          of green chemistry technologies. There are rapidly growing activities 
          in government, industry, and academia in the United States, Italy, the 
          United Kingdom, the Netherlands, Spain, Germany, Japan, China, and many 
          other countries in Europe and Asia, that testify to the importance of 
          green chemistry to the future of the central science of chemistry around 
          the world.
        Organizations and Commissions currently involved in programs in green 
          chemistry at the national or international level include, for example:
        - U.S. Environmental Protection Agency (EPA), with the "Green Chemistry Program" which involves, among others, the National Science Foundation, the American Chemical Society, and the Green Chemistry Institute;
 - European Directorate for R&D (DG Research), which included the goals of sustainable chemistry in the actions and research of the European Fifth Framework Programme;
 - Interuniversity Consortium "Chemistry for the Environment", which groups about 30 Italian universities interested in environmentally benign chemistry and funds their research groups;
 - UK Royal Society of Chemistry, which promotes the concept of green chemistry through a "UK Green Chemistry Network" and the scientific journal Green Chemistry;
 - UNIDO-ICS (International Centre for Science and High Technology of the United Nations Industrial Development Organization) which is developing a global program on sustainable chemistry focusing on catalysis and cleaner technologies with particular attention to developing and emerging countries (the program is also connected with UNIDO network of centers for cleaner production); and
 - Monash University, which is the first organization in Australia to undertake a green chemistry program.
 
Footnotes:
	1. The terminology "green chemistry" 
          or "sustainable chemistry" is the subject of debate. The expressions 
          are intended to convey the same or very similar meanings, but each has 
          its supporters and detractors, since "green" is vividly evocative but 
          may assume an unintended political connotation, whereas "sustainable" 
          can be paraphrased as "chemistry for a sustainable environment", and 
          may be perceived as a less focused and less incisive description of 
          the discipline. Other terms have been proposed, such as "chemistry for 
          the environment" but this juxtaposition of keywords already embraces 
          many diversified fields involving the environment, and does not capture 
          the economic and social implications of sustainability. The Working 
          Party decided to adopt the term green chemistry for the purpose of this 
          overview. This decision does not imply official IUPAC endorsement for 
          the choice. In fact, the IUPAC Committee on Chemistry and Industry (COCI) 
          favors, and will continue to use sustainable chemistry to describe the 
          discipline.
	  2. J. Elkington, < http://www.sustainability.co.uk/sustainability.htm
    